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Home / Primary Antibodies / Polyclonal Antibodies

WEE2 antibody

SKU : BHA10809480

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Mfr.No.	FNab09506
Alternative Names	FLJ16107 ; WEE1homolog2(S.pombe) ; Wee1likeproteinkinase1B ; Wee1likeproteinkinase2 ; WEE1B ; Wee1Bkinase ; WEE2
Background	Oocyte-specific protein tyrosine kinase that phosphorylates and inhibits CDK1 and acts as a key regulator of meiosis during both prophase I and metaphase II. Required to maintain meiotic arrest in oocytes during the germinal vesicle(GV) stage, a long period of quiescence at dictyate prophase I, by phosphorylating CDK1 at 'Tyr-15', leading to inhibit CDK1 activity and prevent meiotic reentry. Also required for metaphase II exit during egg activation by phosphorylating CDK1 at 'Tyr-15', to ensure exit from meiosis in oocytes and promote pronuclear formation(By similarity).
Categories	Primary Antibodies
Clonality	polyclonal
Description	Oocyte-specific protein tyrosine kinase that phosphorylates and inhibits CDK1 and acts as a key regulator of meiosis during both prophase I and metaphase II. Required to maintain meiotic arrest in oocytes during the germinal vesicle (GV) stage, a long period of quiescence at dictyate prophase I, by phosphorylating CDK1 at 'Tyr-15', leading to inhibit CDK1 activity and prevent meiotic reentry. Also required for metaphase II exit during egg activation by phosphorylating CDK1 at 'Tyr-15', to ensure exit from meiosis in oocytes and promote pronuclear formation (By similarity).
Host	Rabbit
Immunogen	WEE1 homolog 2(S. pombe)
Isotype	IgG
Molecular Weight	63 kDa
Reactivity	Human
Regulatory	RUO
Synonyms	FLJ16107, WEE1 homolog 2(S. pombe), Wee1 like protein kinase 1B, Wee1 like protein kinase 2, WEE1B, Wee1B kinase, WEE2

Uniprot	P0C1S8
Gene Id	494551
Research Area	Developmental biology, Signal Transduction
Weight	63kDa

Form	liquid
Format	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)

Applications

ELISA, WB

Description

ELISA ; WB

Dilution

WB	1:200-1:2000

Tested Application

WB: 1:200-1:2000

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SKU	Supplier No.	Size	Your price	Quantity
BHA10809480	FNab09506	100ug	$280		Add to Cart

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