WBS15, also named as LAB, NTAL, WBSCR15, WBSCR5and LAT2(Linker for activation of T-cells family member 2; not SLC7A8/LAT2), is involved in FCER1(high affinity immunoglobulin epsilon receptor)-mediated signaling in mast and myeloid cells. WBS15 is involved in BCR(B-cell antigen receptor)-mediated signaling in B-cells. It is located in the Williams-Beuren syndrome(WBS) critical region. WBS15 has two isoform with MW 27-30 kDa and 12 kDa.
Categories
Primary Antibodies
Cellular Localization
Membrane
Clonality
polyclonal
Description
WBS15, also named as LAB, NTAL, WBSCR15, WBSCR5and LAT2 (Linker for activation of T-cells family member 2; not SLC7A8/LAT2), is involved in FCER1 (high affinity immunoglobulin epsilon receptor)-mediated signaling in mast and myeloid cells. WBS15 is involved in BCR (B-cell antigen receptor)-mediated signaling in B-cells. It is located in the Williams-Beuren syndrome (WBS) critical region. WBS15 has two isoform with MW 27-30 kDa and 12 kDa.
Host
Rabbit
Immunogen
linker for activation of T cells family, member 2
Isotype
IgG
Molecular Weight
27 kDa,14 kDa
Reactivity
Human, Mouse
Regulatory
RUO
Subcellular Location
Cell membrane
Synonyms
HSPC046, LAB, LAT2, Non T cell activation linker, NTAL, WBS15, WBSCR15, WBSCR5, WSCR5
Uniprot
Q9GZY6
Research Area
Immunology, Signal Transduction
Weight
27kDa,observed 27kDa,14kDa
Form
liquid
Format
liquid
Purification
Immunogen affinity purified
Purity
>=95% as determined by SDS-PAGE
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)