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Home / Primary Antibodies / Polyclonal Antibodies

VPS8 antibody

SKU : BHA10809425

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Mfr.No.	FNab09451
Alternative Names	FLJ32099 ; KIAA0804 ; VPS8
Background	Plays a role in vesicle-mediated protein trafficking of the endocytic membrane transport pathway. Believed to act as a component of the putative CORVET endosomal tethering complexes which is proposed to be involved in the Rab5-to-Rab7 endosome conversion probably implicating MON1A/B, and via binding SNAREs and SNARE complexes to mediate tethering and docking events during SNARE-mediated membrane fusion. The CORVET complex is proposed to function as a Rab5 effector to mediate early endosome fusion probably in specific endosome subpopulations(PubMed:25266290). Functions predominantly in APPL1-containing endosomes(PubMed:25266290).
Categories	Primary Antibodies
Cellular Localization	Endosome
Clonality	polyclonal
Description	Plays a role in vesicle-mediated protein trafficking of the endocytic membrane transport pathway. Believed to act as a component of the putative CORVET endosomal tethering complexes which is proposed to be involved in the Rab5-to-Rab7 endosome conversion probably implicating MON1A/B, and via binding SNAREs and SNARE complexes to mediate tethering and docking events during SNARE-mediated membrane fusion. The CORVET complex is proposed to function as a Rab5 effector to mediate early endosome fusion probably in specific endosome subpopulations (PubMed:25266290). Functions predominantly in APPL1-containing endosomes (PubMed:25266290).
Host	Rabbit
Immunogen	vacuolar protein sorting 8 homolog
Isotype	IgG
Molecular Weight	151 kDa
Reactivity	Human, Mouse, Rat
Regulatory	RUO
Subcellular Location	Endosome
Synonyms	FLJ32099, KIAA0804, VPS8

Uniprot	Q8N3P4
Gene Id	23355
Research Area	Signal Transduction
Weight	151kDa

Form	liquid
Format	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)

Applications

ELISA, WB, IF, IP

Description

ELISA ; WB ; IF ; IP

Dilution

WB	1:500-1:5000
IP	1:200-1:2000
IF	1:10-1:100

Tested Application

WB: 1:500-1:5000?IP: 1:200-1:2000; IF: 1:10-1:100

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SKU	Supplier No.	Size	Your price	Quantity
BHA10809425	FNab09451	100ug	$260		Add to Cart

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