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Home / Primary Antibodies / Polyclonal Antibodies

VPS52 antibody

SKU : BHA10809421

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Mfr.No.	FNab09447
Alternative Names	ARE1 ; dJ1033B10.5 ; DKFZp547I194 ; RP51033B10 ; SAC2 ; SACM2L ; VPS52
Background	Acts as component of the GARP complex that is involved in retrograde transport from early and late endosomes to the trans-Golgi network(TGN). The GARP complex is required for the maintenance of the cycling of mannose 6-phosphate receptors between the TGN and endosomes, this cycling is necessary for proper lysosomal sorting of acid hydrolases such as CTSD(PubMed:15878329, PubMed:18367545). Acts as component of the EARP complex that is involved in endocytic recycling. The EARP complex associates with Rab4-positive endosomes and promotes recycling of internalized transferrin receptor(TFRC) to the plasma membrane(PubMed:25799061).
Categories	Primary Antibodies
Cellular Localization	Endosome, Golgi Apparatus, Membrane
Clonality	polyclonal
Description	Acts as component of the GARP complex that is involved in retrograde transport from early and late endosomes to the trans-Golgi network (TGN). The GARP complex is required for the maintenance of the cycling of mannose 6-phosphate receptors between the TGN and endosomes, this cycling is necessary for proper lysosomal sorting of acid hydrolases such as CTSD (PubMed:15878329, PubMed:18367545). Acts as component of the EARP complex that is involved in endocytic recycling. The EARP complex associates with Rab4-positive endosomes and promotes recycling of internalized transferrin receptor (TFRC) to the plasma membrane (PubMed:25799061).
Host	Rabbit
Immunogen	vacuolar protein sorting 52 homolog
Isotype	IgG
Molecular Weight	82 kDa
Reactivity	Human, Mouse, Rat
Regulatory	RUO
Subcellular Location	Endosome, Golgi apparatus, Membrane
Synonyms	ARE1, dJ1033B10.5, DKFZp547I194, RP5 1033B10, SAC2, SACM2L, VPS52

Uniprot	Q8N1B4
Gene Id	6293
Research Area	Signal Transduction
Weight	82kDa

Form	liquid
Format	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)

Applications

ELISA, WB, IHC, IF, IP

Description

ELISA ; WB ; IHC ; IF ; IP

Dilution

WB	1:200-1:2000
IP	1:500-1:5000
IHC	1:20-1:200
IF	1:10-1:100

Tested Application

WB: 1:200-1:2000?IP: 1:500-1:5000?IHC: 1:20-1:200; IF: 1:10-1:100

Manual	FNab09447.pdf

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SKU	Supplier No.	Size	Your price	Quantity
BHA10809421	FNab09447	100ug	$260		Add to Cart

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