PIK3C3(Phosphatidylinositol 3-kinase catalytic subunit type 3) is also named as VPS34 and belongs to the PI3/PI4-kinase family.It is a catalytic subunit of the PI3K complex that mediates formation of phosphatidylinositol 3-phosphate which plays a key role in initiation and maturation of autophagosomes.It can form a dimer(PMID:20339072).
Clonality
polyclonal
Host
Rabbit
Immunogen
phosphoinositide-3-kinase, class 3
Immunogen Region
phosphoinositide-3-kinase, class 3
Isotype
IgG
Molecular Weight
100 kDa
Reactivity
Human, Mouse, Rat
Recommended Dilution
WB: 1:200-1:2000; IHC: 1:20-1?200
Synonyms
HVps34, PI 3 Kinase Class 3, PI 3-kinase p100, PI3K p100, PI3K type 3, PIK3C3, PtdIns 3 kinase type 3, VPS34
Uniprot
Q8NEB9
Gene Id
5289
Research Area
Signal Transduction, Metabolism
Form
liquid
Purification
Immunogen affinity purified
Purity
>=95% as determined by SDS-PAGE
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)
Tested Application
WB: 1:200-1:2000; IHC: 1:20-1?200
Product Manual
<a href="https://www.fn-test.com/content/uploads/product/manuals/antibody/FNab09438.pdf" target="_blank">Data Sheet</ a>