Vitronectin is a 75-kDa glycoprotein present in blood and in the extracellular matrix(PMID: 10399314). Vitronectin is a multifunctional glycoprotein that mediates cell-to-substrate adhesion, inhibits the cytolytic action of the terminal complement cascade in vitro and binds to several serine protease inhibitors of the serpin family(PMID: 1372588).
Categories
Primary Antibodies
Cellular Localization
Secreted
Clonality
polyclonal
Description
Vitronectin is a 75-kDa glycoprotein present in blood and in the extracellular matrix (PMID: 10399314). Vitronectin is a multifunctional glycoprotein that mediates cell-to-substrate adhesion, inhibits the cytolytic action of the terminal complement cascade in vitro and binds to several serine protease inhibitors of the serpin family (PMID: 1372588).
Host
Rabbit
Immunogen
vitronectin
Isotype
IgG
Reactivity
Human, Mouse, Rat
Regulatory
RUO
Subcellular Location
Secreted
Synonyms
S protein, Serum spreading factor, V75, vitronectin, VN, VNT, VTN
Uniprot
P04004
Gene Id
7448
Research Area
Immunology, Cardiovascular, Signal Transduction
Weight
54kDa,observed 75kDa
Form
liquid
Format
liquid
Purification
Immunogen affinity purified
Purity
>=95% as determined by SDS-PAGE
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)