Vitamin D binding protein is a sparsely glycosylated serum protein responsible for highly specific binding and tissue-specific delivery of vitamin D and its metabolites. In addition, it is also an actin scavenger, and is the precursor to the immunomodulatory protein, Gc-MAF. Vitamin D binding protein has been proposed to have significant roles in C5a chemotaxis, osteoclast development and possibly in macrophage activation/recruitment.
Categories
Primary Antibodies
Cellular Localization
Secreted
Clonality
monoclonal
Host
Mouse
Immunogen
group-specific component(vitamin D binding protein)
Isotype
IgG1
Molecular Weight
75 kDa
Reactivity
Human
Regulatory
RUO
Subcellular Location
Secreted
Synonyms
DBP, DBP/GC, GC, Gc globulin, VDBP,GC, Vitamin D binding protein
Uniprot
P02774
Gene Id
2638
Clone No
2H10
Research Area
Metabolism
Weight
53kDa
Form
liquid
Format
liquid
Purification
Protein A+G purification
Purity
>=95% as determined by SDS-PAGE
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)