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Home / Primary Antibodies / Polyclonal Antibodies

Visfatin antibody

SKU : BHA10809387

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Mfr.No.	FNab09412
Alternative Names	1110035O14Rik ; DKFZp666B131 ; NAmPRTase ; NAMPT ; PBEF ; PBEF1 ; PreBcellenhancingfactor ; VF ; VISFATIN
Background	Nicotinamide phosphoribosyltransferase(NAMPT) has two usual synonyms termed Visfatin and PBEF. Its primary role is to catalyze the condensation of nicotinamide with 5-phosphoribosyl-1-pyrophosphate to yield nicotinamide mononucleotide, an intermediate in the biosynthesis of NAD, which is the rate limiting component in the mammalian NAD biosynthesis pathway. NAMPT is localized in cytoplasm and expressed in large amounts in bone marrow, liver tissue, and muscle tissues. NAMPT inhibits neutrophil apoptosis in experimental inflammation and clinical sepsis. NAMPT levels are altered in plasma of patients with type 2 diabetes mellitus(T2DM), and it is now evidenced that NAMPT may plays a role in lipid metabolism.
Categories	Primary Antibodies
Cellular Localization	Cytoplasm, Nucleus, Secreted
Clonality	polyclonal
Description	Nicotinamide phosphoribosyltransferase(NAMPT) has two usual synonyms termed Visfatin and PBEF. Its primary role is to catalyze the condensation of nicotinamide with 5-phosphoribosyl-1-pyrophosphate to yield nicotinamide mononucleotide, an intermediate in the biosynthesis of NAD, which is the rate limiting component in the mammalian NAD biosynthesis pathway. NAMPT is localized in cytoplasm and expressed in large amounts in bone marrow, liver tissue, and muscle tissues. NAMPT inhibits neutrophil apoptosis in experimental inflammation and clinical sepsis. NAMPT levels are altered in plasma of patients with type 2 diabetes mellitus (T2DM), and it is now evidenced that NAMPT may plays a role in lipid metabolism.
Host	Rabbit
Immunogen	nicotinamide phosphoribosyltransferase
Isotype	IgG
Molecular Weight	55 kDa
Reactivity	Human, Mouse, Rat
Regulatory	RUO
Subcellular Location	Cytoplasm, Nucleus, Secreted
Synonyms	1110035O14Rik, DKFZp666B131, NAmPRTase, NAMPT, PBEF, PBEF1, Pre B cell enhancing factor, VF, VISFATIN

Uniprot	P43490
Research Area	Cardiovascular, Metabolism, Signal Transduction, Neuroscience
Weight	55kDa

Form	liquid
Format	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)

Applications

ELISA, IHC, WB, IP

Description

ELISA ; IHC ; WB ; IP

Dilution

WB	1:500-1:5000
IHC	1:20-1:200
IP	1:500-1:5000

Tested Application

WB: 1:500-1:2000; IHC: 1:20-1:200; IP: 1:500-1:2000

Manual	FNab09412.pdf

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SKU	Supplier No.	Size	Your price	Quantity
BHA10809387	FNab09412	100ug	$240		Add to Cart

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