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Home / Primary Antibodies / Polyclonal Antibodies

Villin antibody

SKU : BHA10809382

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Mfr.No.	FNab09406
Alternative Names	VIL ; VIL1 ; Villin ; villin1
Background	Villin 1(VIL1) is a 95-kd F-actin bundling and severing protein and its expression is restricted to epithelial cells with a brush border, like epithelial cells of the intestinal mucosa, gall bladder, renal proximal tubules and ductuli efferentes of the testis. VIL1 has been reported to be an epithelial cell-specific anti-apoptotic protein, and to have an important function in regulating actin dynamics, cell morphology, epithelial-to-mesenchymal transitions, cell migration and cell survival. In addition, VIL1 is a useful diagnostic marker for of various cancer, like cervical and endometrial adenocarcinomas, renal cell carcinoma. VIL1 was recently identified as a novel biomarker predictive for postoperative recurrence and poorer prognosis of high serum AFP associated HCC.
Categories	Primary Antibodies
Cellular Localization	Cell Projection, Cytoplasm, cytoskeleton
Clonality	polyclonal
Description	Villin 1 (VIL1) is a 95-kd F-actin bundling and severing protein and its expression is restricted to epithelial cells with a brush border, like epithelial cells of the intestinal mucosa, gall bladder, renal proximal tubules and ductuli efferentes of the testis. VIL1 has been reported to be an epithelial cell-specific anti-apoptotic protein, and to have an important function in regulating actin dynamics, cell morphology, epithelial-to-mesenchymal transitions, cell migration and cell survival. In addition, VIL1 is a useful diagnostic marker for of various cancer, like cervical and endometrial adenocarcinomas, renal cell carcinoma. VIL1 was recently identified as a novel biomarker predictive for postoperative recurrence and poorer prognosis of high serum AFP associated HCC.
Host	Rabbit
Immunogen	villin 1
Isotype	IgG
Molecular Weight	93 kDa
Reactivity	Human, Mouse, Rat
Regulatory	RUO
Subcellular Location	Cell projection, Cytoplasm, Cytoskeleton
Synonyms	VIL, VIL1, Villin, villin 1

Uniprot	P09327
Gene Id	7429
Research Area	Cancer, Immunology
Weight	93kDa

Form	liquid
Format	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)

Applications

ELISA, WB, IHC, IF

Description

ELISA ; WB ; IHC ; IF

Dilution

WB	1:1000-1:10000
IHC	1:50-1:8000
IF	1:20-1:200
IP	1:200-1:1000

Tested Application

WB: 1:1000-1:10000; IHC: 1:50-1:8000; IF: 1:20-1:200; IP: 1:200-1:1000

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SKU	Supplier No.	Size	Your price	Quantity
BHA10809382	FNab09406	100ug	$260		Add to Cart

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