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Home / Primary Antibodies / Polyclonal Antibodies

VHL antibody

SKU : BHA10809379

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Mfr.No.	FNab09402
Alternative Names	HRCA1 ; ProteinG7 ; pVHL ; RCA1 ; VHL ; VHL1 ; VonHippe-Lindau
Background	Involved in the ubiquitination and subsequent proteasomal degradation via the von Hippel-Lindau ubiquitination complex. Seems to act as a target recruitment subunit in the E3 ubiquitin ligase complex and recruits hydroxylated hypoxia-inducible factor(HIF) under normoxic conditions. Involved in transcriptional repression through interaction with HIF1A, HIF1AN and histone deacetylases. Ubiquitinates, in an oxygen-responsive manner, ADRB2.
Categories	Primary Antibodies
Cellular Localization	Cytoplasm, Membrane, Nucleus
Clonality	polyclonal
Description	Involved in the ubiquitination and subsequent proteasomal degradation via the von Hippel-Lindau ubiquitination complex. Seems to act as a target recruitment subunit in the E3 ubiquitin ligase complex and recruits hydroxylated hypoxia- inducible factor (HIF) under normoxic conditions. Involved in transcriptional repression through interaction with HIF1A, HIF1AN and histone deacetylases. Ubiquitinates, in an oxygen-responsive manner, ADRB2.
Host	Rabbit
Immunogen	von Hippel-Lindau tumor suppressor
Isotype	IgG
Molecular Weight	18-24 kDa
Reactivity	Human, Mouse, Rat
Regulatory	RUO
Subcellular Location	Cytoplasm, Membrane, Nucleus
Synonyms	HRCA1, Protein G7, pVHL, RCA1, VHL, VHL1, Von Hippe-Lindau

Uniprot	P40337
Gene Id	7428
Research Area	Cancer, Metabolism
Weight	20kDa

Form	liquid
Format	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)

Applications

ELISA, IF, IHC

Description

ELISA ; IF ; IHC

Dilution

IF	1:10-1:100
IHC	1:20-1:200

Tested Application

WB: 1:500-1:2000; IHC: 1:50-1:200; IF: 1:20-1:200

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SKU	Supplier No.	Size	Your price	Quantity
BHA10809379	FNab09402	100ug	$260		Add to Cart

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