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Home / Primary Antibodies / Polyclonal Antibodies

VEGF antibody

SKU : BHA10809369

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Mfr.No.	FNab09391
Alternative Names	LVEGFA ; MVCD1 ; Vascularpermeabilityfactor ; VEGF ; VEGFA ; VEGFA ; VPF
Background	VEGFA, also named as VEGF or VPF, belongs to the PDGF/VEGF growth factor family. It is a growth factor active in angiogenesis, vasculogenesis and endothelial cell growth. VEGFA induces endothelial cell proliferation, promotes cell migration, inhibits apoptosis and induces permeabilization of blood vessels. It binds to the FLT1/VEGFR1 and KDR/VEGFR2 receptors, heparan sulfate and heparin. Defects in VEGFA are a cause of susceptibility to microvascular complications of diabetes type 1(MVCD1). VEGFA has 13 isoforms with MW 16kd to 45kd. Some isoforms has homodimer form, such as VEGFA189(38kd), VEFGA110(34kd). VEGFA is a 34kd to 42kd, dimeric, disulfide-bound glycoprotein. VEGF-A exists in at least seven homodimeric isoforms. The monomers consist of 121, 145, 148, 165, 183, 189, or 206 amino acids(PMID:15602010).
Categories	Primary Antibodies
Cellular Localization	Secreted
Clonality	polyclonal
Description	VEGFA, also named as VEGF or VPF, belongs to the PDGF/VEGF growth factor family. It is a growth factor active in angiogenesis, vasculogenesis and endothelial cell growth. VEGFA induces endothelial cell proliferation, promotes cell migration, inhibits apoptosis and induces permeabilization of blood vessels. It binds to the FLT1/VEGFR1 and KDR/VEGFR2 receptors, heparan sulfate and heparin. Defects in VEGFA are a cause of susceptibility to microvascular complications of diabetes type 1 (MVCD1). VEGFA has 13 isoforms with MW 16kd to 45kd. Some isoforms has homodimer form, such as VEGFA189(38kd), VEFGA110(34kd). VEGFA is a 34kd to 42kd, dimeric, disulfide-bound glycoprotein. VEGF-A exists in at least seven homodimeric isoforms. The monomers consist of 121, 145, 148, 165, 183, 189, or 206 amino acids(PMID:15602010 ). This antibody can recognize all the isoforms of VEFGA.
Host	Rabbit
Immunogen	vascular endothelial growth factor A
Isotype	IgG
Molecular Weight	15-27kDa, 34-45kDa
Reactivity	Human, Mouse, Rat
Regulatory	RUO
Subcellular Location	Secreted
Synonyms	L VEGFA, MVCD1, Vascular permeability factor, VEGF, VEGF A, VEGFA, VPF

Uniprot	P15692
Gene Id	7422
Research Area	Developmental biology, Signal Transduction, Cardiovascular, Cancer, Immunology
Weight	27kDa

Form	liquid
Format	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)

Applications

ELISA, IHC, IF, IP, WB

Description

ELISA ; IHC ; IF ; IP ; WB

Dilution

WB	1:200-1:2000
IP	1:200-1:2000
IF	1:10-1:100
IHC	1:50-1:500

Tested Application

WB: 1:200-1:2000; IF: 1:10-1:100; IHC: 1:50-1:500

Manual	FNab09391.pdf

No Description Available.

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SKU	Supplier No.	Size	Your price	Quantity
BHA10809369	FNab09391	100ug	$260		Add to Cart

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