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Home / Primary Antibodies / Monoclonal Antibodies

VEGF antibody

SKU : BHA10809922

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Mfr.No.	FNab09933
Background	VEGFA, also named as VEGF or VPF, belongs to the PDGF/VEGF growth factor family. It is a growth factor active in angiogenesis, vasculogenesis and endothelial cell growth. VEGFA induces endothelial cell proliferation, promotes cell migration, inhibits apoptosis and induces permeabilization of blood vessels. It binds to the FLT1/VEGFR1 and KDR/VEGFR2 receptors, heparan sulfate and heparin. Defects in VEGFA are a cause of susceptibility to microvascular complications of diabetes type 1(MVCD1). VEGFA has 13 isoforms with MW 16kd to 45kd. Some isoforms has homodimer form, such as VEGFA189(38kd), VEFGA110(34kd). VEGFA is a 34kd to 42kd, dimeric, disulfide-bound glycoprotein. VEGF-A exists in at least seven homodimeric isoforms. The monomers consist of 121, 145, 148, 165, 183, 189, or 206 amino acids(PMID:15602010). This antibody can recognize all the isoforms of VEFGA.
Clonality	monoclonal
Host	Mouse
Immunogen	vascular endothelial growth factor A
Immunogen Region	vascular endothelial growth factor A
Isotype	IgG2b
Molecular Weight	45 kDa
Reactivity	Human
Recommended Dilution	WB: 1:1000-1:4000; IHC: 1:50-1:500
Synonyms	L VEGFA, MVCD1, Vascular permeability factor, VEGF, VEGF A, VEGFA, VPF

Uniprot	P15692
Clone No	5H5
Research Area	Developmental biology, Signal Transduction, Cardiovascular, Cancer, Immunology

Form	liquid
Purification	protein A+G purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)

Tested Application	WB: 1:1000-1:4000; IHC: 1:50-1:500

Product Manual	<a href="https://www.fn-test.com/content/uploads/product/manuals/antibody/FNab09933.pdf" target="_blank">Data Sheet</ a>

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SKU	Supplier No.	Size	Your price	Quantity
BHA10809922	FNab09933	100ug	$280		Add to Cart

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