Forms a channel through the mitochondrial outer membrane that allows diffusion of small hydrophilic molecules. The channel adopts an open conformation at low or zero membrane potential and a closed conformation at potentials above 30-40 mV. The open state has a weak anion selectivity whereas the closed state is cation-selective.
Categories
Primary Antibodies
Cellular Localization
Mitochondrion Outer Membrane
Clonality
polyclonal
Description
Forms a channel through the mitochondrial outer membrane that allows diffusion of small hydrophilic molecules. The channel adopts an open conformation at low or zero membrane potential and a closed conformation at potentials above 30-40 mV. The open state has a weak anion selectivity whereas the closed state is cation- selective.
Host
Rabbit
Immunogen
voltage-dependent anion channel 2
Isotype
IgG
Molecular Weight
32 kDa
Reactivity
Human, Mouse, Rat
Regulatory
RUO
Subcellular Location
Mitochondrion outer membrane
Synonyms
FLJ23841, hVDAC2, VDAC 2, VDAC2
Uniprot
P45880
Gene Id
7417
Research Area
Signal Transduction, Cancer, Metabolism
Weight
32kDa
Form
liquid
Format
liquid
Purification
Immunogen affinity purified
Purity
>=95% as determined by SDS-PAGE
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)