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Home / Primary Antibodies / Polyclonal Antibodies

VDAC1/Porin antibody

SKU : BHA10809365

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Mfr.No.	FNab09385
Alternative Names	HVDAC1 ; Plasmalemmalporin ; Porin ; PORIN31HL ; Porin31HL ; Porin31HM ; VDAC ; VDAC1 ; VDAC1
Background	This gene encodes a voltage-dependent anion channel protein that is a major component of the outer mitochondrial membrane. The encoded protein facilitates the exchange of metabolites and ions across the outer mitochondrial membrane and may regulate mitochondrial functions. This protein also forms channels in the plasma membrane and may be involved in transmembrane electron transport. Alternate splicing results in multiple transcript variants. Multiple pseudogenes of this gene are found on chromosomes 1, 2 3, 6, 9, 12, X and Y.
Categories	Primary Antibodies
Cellular Localization	Mitochondrion Outer Membrane
Clonality	polyclonal
Description	VDAC1, also named as VDAC, Porin 31HM, Porin 31HL and Plasmalemmal porin, belongs to the eukaryotic mitochondrial porin family. It adopts an open conformation at low or zero membrane potential and a closed conformation at potentials above 30-40 mV, to form a channel through the mitochondrial outer membrane and also the plasma membrane. Unlike other membrane transport proteins, porins are large enough to allow passive diffusion. It is a 31kd membrane protein conserved in chimpanzee, dog, cow, mouse, rat, chicken, and zebrafish.
Host	Rabbit
Immunogen	voltage-dependent anion channel 1
Isotype	IgG
Molecular Weight	Refer to figures
Reactivity	Human, Mouse
Regulatory	RUO
Subcellular Location	Mitochondrion outer membrane
Synonyms	HVDAC1, Plasmalemmal porin, Porin, PORIN 31 HL, Porin 31HL, Porin 31HM, VDAC, VDAC 1, VDAC1

Uniprot	P21796
Gene Id	7416
Research Area	Signal Transduction, Cancer, Metabolism
Weight	31kDa

Form	liquid
Format	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Applications

ELISA, WB, IHC, IP, IF

Description

ELISA ; WB ; IHC ; IP ; IF

Dilution

WB	1:500-1:5000
IP	1:500-1:5000
IHC	1:50-1:200
IF	1:20-1:200

Tested Application

WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:50 - 1:200

Manual	FNab09385.pdf

No Description Available.

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SKU	Supplier No.	Size	Your price	Quantity
BHA10809365	FNab09385	100ug	$260		Add to Cart

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