Acts as a deubiquitinating enzyme. Necessary for VCP-mediated reassembly of Golgi stacks after mitosis. May play a role in VCP-mediated formation of transitional endoplasmic reticulum(tER). Mediates dissociation of the ternary complex containing STX5A, NSFL1C and VCP(By similarity). Hydrolyzes 'Lys-11'-and 'Lys-48'-linked polyubiquitin chains.
Categories
Primary Antibodies
Cellular Localization
endoplasmic reticulum, Golgi Apparatus
Clonality
polyclonal
Description
Acts as a deubiquitinating enzyme. Necessary for VCP- mediated reassembly of Golgi stacks after mitosis. May play a role in VCP-mediated formation of transitional endoplasmic reticulum (tER). Mediates dissociation of the ternary complex containing STX5A, NSFL1C and VCP (By similarity). Hydrolyzes 'Lys-11'- and 'Lys-48'-linked polyubiquitin chains.
Host
Rabbit
Immunogen
valosin containing protein(p97)/p47 complex interacting protein 1
Isotype
IgG
Molecular Weight
135 kDa
Reactivity
Human, Mouse, Rat
Regulatory
RUO
Subcellular Location
Endoplasmic reticulum, Golgi apparatus
Synonyms
VCPIP1, FLJ23132, KIAA1850, DUBA3, DKFZp686G038
Uniprot
Q96JH7
Gene Id
80124
Research Area
Epigenetics, Metabolism
Weight
134kDa,observed 55kDa,90kDa,135kDa
Form
liquid
Format
liquid
Purification
Immunogen affinity purified
Purity
>=95% as determined by SDS-PAGE
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)