The protein encoded by this gene is a type IV membrane protein found in plasma and intracellular vesicle membranes. The encoded protein is found as a homodimer and as a heterodimer with VAPA. This protein also can interact with VAMP1 and VAMP2 and may be involved in vesicle trafficking.
Categories
Primary Antibodies
Cellular Localization
endoplasmic reticulum, Membrane
Clonality
polyclonal
Description
Participates in the endoplasmic reticulum unfolded protein response (UPR) by inducing ERN1/IRE1 activity. Involved in cellular calcium homeostasis regulation.
Host
Rabbit
Immunogen
VAMP (vesicle-associated membrane protein)-associated protein B and C