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Home / Primary Antibodies / Polyclonal Antibodies

VANGL2 antibody

SKU : BHA10809348

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Mfr.No.	FNab09367
Alternative Names	KIAA1215 ; Looptailprotein1homolog ; LPP1 ; LTAP ; STB1 ; STBM ; STBM1 ; Strabismus1 ; VanGoghlikeprotein2 ; Vanglikeprotein2 ; VANGL2
Background	The protein encoded by this gene is a membrane protein involved in the regulation of planar cell polarity, especially in the stereociliary bundles of the cochlea. The encoded protein transmits directional signals to individual cells or groups of cells in epithelial sheets. This protein is also involved in the development of the neural plate.
Categories	Primary Antibodies
Cellular Localization	Membrane
Clonality	polyclonal
Description	Involved in the control of early morphogenesis and patterning of both axial midline structures and the development of neural plate. Plays a role in the regulation of planar cell polarity, particularly in the orientation of stereociliary bundles in the cochlea. Required for polarization and movement of myocardializing cells in the outflow tract and seems to act via RHOA signaling to regulate this process. Required for cell surface localization of FZD3 and FZD6 in the inner ear (By similarity).
Host	Rabbit
Immunogen	vang-like 2 (van gogh, Drosophila)
Isotype	IgG
Molecular Weight	70 kDa
Reactivity	Human, Mouse, Rat
Regulatory	RUO
Subcellular Location	Cell membrane
Synonyms	KIAA1215, Loop tail protein 1 homolog, LPP1, LTAP, STB1, STBM, STBM1, Strabismus 1, Van Gogh like protein 2, Vang like protein 2, VANGL2

Uniprot	Q9ULK5
Gene Id	57216
Research Area	Developmental biology, Cardiovascular
Weight	60kDa,observed 60kDa,70kDa

Form	liquid
Format	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Applications

ELISA, WB, IHC, IP, IF

Description

ELISA ; WB ; IHC ; IP ; IF

Dilution

WB	1:200-1:2000
IHC	1:20-1:200
IF	1:20-1:200
IP	1:500-1:5000

Tested Application

WB: 1:500 - 1:2000; IHC: 1:50 - 1:200

Manual	FNab09367.pdf

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SKU	Supplier No.	Size	Your price	Quantity
BHA10809348	FNab09367	100ug	$260		Add to Cart

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