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Home / Primary Antibodies / Polyclonal Antibodies

USP49 antibody

SKU : BHA10809320

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Mfr.No.	FNab09338
Alternative Names	Deubiquitinatingenzyme49 ; Ubiquitinthiolesterase49 ; USP49
Background	Specifically deubiquitinates histone H2B at 'Lys-120'(H2BK120Ub). H2BK120Ub is a specific tag for epigenetic transcriptional activation and acts as a regulator of mRNA splicing. Deubiquitination is required for efficient cotranscriptional splicing of a large set of exons.
Categories	Primary Antibodies
Cellular Localization	Nucleus
Clonality	polyclonal
Description	Specifically deubiquitinates histone H2B at 'Lys-120' (H2BK120Ub). H2BK120Ub is a specific tag for epigenetic transcriptional activation and acts as a regulator of mRNA splicing. Deubiquitination is required for efficient cotranscriptional splicing of a large set of exons.
Host	Rabbit
Immunogen	ubiquitin specific peptidase 49
Isotype	IgG
Molecular Weight	73 kDa
Reactivity	Human, Mouse, Rat
Regulatory	RUO
Subcellular Location	Nucleus
Synonyms	Deubiquitinating enzyme 49, Ubiquitin thiolesterase 49, USP49

Antigen	USP49
Uniprot	Q70CQ1
Gene Id	25862
Research Area	Epigenetics, Metabolism
Weight	73kDa，Observed 55kDa，73kDa

Form	liquid
Format	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)

Applications

ELISA, WB, IHC

Description

ELISA ; WB ; IHC

Dilution

WB	1:500-1:5000
IHC	1:20-1:200

Tested Application

WB: 1:500-1:5000; IHC: 1?20-1?200

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SKU	Supplier No.	Size	Your price	Quantity
BHA10809320	FNab09338	100ug	$260		Add to Cart

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