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Home / Primary Antibodies / Polyclonal Antibodies

USP34 antibody

SKU : BHA10809309

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Mfr.No.	FNab09327
Alternative Names	Deubiquitinatingenzyme34 ; FLJ43910 ; KIAA0570 ; KIAA0729 ; Ubiquitinthiolesterase34 ; USP34
Background	Ubiquitin hydrolase that can remove conjugated ubiquitin from AXIN1 and AXIN2, thereby acting as a regulator of Wnt signaling pathway. Acts as an activator of the Wnt signaling pathway downstream of the beta-catenin destruction complex by deubiquitinating and stabilizing AXIN1 and AXIN2, leading to promote nuclear accumulation of AXIN1 and AXIN2 and positively regulate beta-catenin(CTNBB1)-mediated transcription. Recognizes and hydrolyzes the peptide bond at the C-terminal Gly of ubiquitin. Involved in the processing of poly-ubiquitin precursors as well as that of ubiquitinated proteins.
Categories	Primary Antibodies
Cellular Localization	Cytosol
Clonality	polyclonal
Description	Ubiquitin hydrolase that can remove conjugated ubiquitin from AXIN1 and AXIN2, thereby acting as a regulator of Wnt signaling pathway. Acts as an activator of the Wnt signaling pathway downstream of the beta-catenin destruction complex by deubiquitinating and stabilizing AXIN1 and AXIN2, leading to promote nuclear accumulation of AXIN1 and AXIN2 and positively regulate beta-catenin (CTNBB1)-mediated transcription. Recognizes and hydrolyzes the peptide bond at the C-terminal Gly of ubiquitin. Involved in the processing of poly-ubiquitin precursors as well as that of ubiquitinated proteins.
Host	Rabbit
Immunogen	ubiquitin specific peptidase 34
Isotype	IgG
Molecular Weight	47 kDa
Reactivity	Human, Mouse
Regulatory	RUO
Subcellular Location	cytosol
Synonyms	Deubiquitinating enzyme 34, FLJ43910, KIAA0570, KIAA0729, Ubiquitin thiolesterase 34, USP34

Uniprot	Q70CQ2
Gene Id	9736
Research Area	Epigenetics, Metabolism
Weight	47kDa

Form	liquid
Format	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)

Applications

ELISA, WB, IHC

Description

ELISA ; WB ; IHC

Dilution

WB	1:500-1:5000
IP	1:200-1:2000
IHC	1:20-1:200

Tested Application

WB: 1:500-1:5000; IP: 1?200-1?2000; IHC: 1?20-1?200

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SKU	Supplier No.	Size	Your price	Quantity
BHA10809309	FNab09327	100ug	$280		Add to Cart

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