Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III, the branch point for the various sub-pathways leading to the wide diversity of porphyrins. Porphyrins act as cofactors for a multitude of enzymes that perform a variety of processes within the cell such as methionine synthesis(vitamin B12) or oxygen transport(heme).
Categories
Primary Antibodies
Cellular Localization
Cytosol, Itochondrion
Clonality
polyclonal
Description
Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III, the branch point for the various sub-pathways leading to the wide diversity of porphyrins. Porphyrins act as cofactors for a multitude of enzymes that perform a variety of processes within the cell such as methionine synthesis (vitamin B12) or oxygen transport (heme).
Host
Rabbit
Immunogen
uroporphyrinogen III synthase
Isotype
IgG
Molecular Weight
29 kDa
Reactivity
Human, Mouse, Rat
Regulatory
RUO
Subcellular Location
cytosol,mitochondrion
Synonyms
UROIIIS, uroporphyrinogen III synthase, UROS
Uniprot
P10746
Gene Id
7390
Research Area
Metabolism
Weight
29kDa
Form
liquid
Format
liquid
Purification
Immunogen affinity purified
Purity
>=95% as determined by SDS-PAGE
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)