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Home / Primary Antibodies / Polyclonal Antibodies

uPA antibody

SKU : BHA10809254

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Mfr.No.	FNab09267
Alternative Names	ATF ; PLAU ; Uplasminogenactivator ; uPA ; URK
Background	PLAU(Urokinase-type plasminogen activator) is also named as uPA and belongs to the peptidase S1 family.UPA initiates a proteolytic cascade, which degrades extracellular matrix during tissue growth and remodelling.The secreted proform of UPA is activated after binding to a specific high affinity cell surface receptor. Secreted UPA is exposed to rapid inactivation in the pericellular space by plasminogen activator inhibitor-1(PAI-1), which is stored in the extracellular matrix bound to vitronectin(PMID:9665342).It has 2 isoforms produced by alternative splicing.Defects in PLAU are the cause of Quebec platelet disorder(QPD).
Categories	Primary Antibodies
Cellular Localization	Secreted
Clonality	polyclonal
Description	PLAU(Urokinase-type plasminogen activator) is also named as uPA and belongs to the peptidase S1 family.UPA initiates a proteolytic cascade, which degrades extracellular matrix during tissue growth and remodelling.The secreted proform of UPA is activated after binding to a specific high affinity cell surface receptor. Secreted UPA is exposed to rapid inactivation in the pericellular space by plasminogen activator inhibitor-1 (PAI-1), which is stored in the extracellular matrix bound to vitronectin(PMID:9665342).It has 2 isoforms produced by alternative splicing.Defects in PLAU are the cause of Quebec platelet disorder (QPD).
Host	Rabbit
Immunogen	plasminogen activator, urokinase
Isotype	IgG
Molecular Weight	54 kDa
Reactivity	Human, Mouse, Rat
Regulatory	RUO
Subcellular Location	Secreted
Synonyms	ATF, PLAU, U plasminogen activator, uPA, URK

Uniprot	P00749
Gene Id	5328
Research Area	Immunology, Cardiovascular, Signal Transduction
Weight	50kDa

Form	liquid
Format	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)

Applications

ELISA, WB, IHC, IP, IF

Description

ELISA ; WB ; IHC ; IP ; IF

Dilution

WB	1:200-1:2000
IHC	1:20-1:200
IF	1:20-1:200
IP	1:500-1:5000

Tested Application

WB: 1:500-1:1000; IHC?1:20-1:200?IF: 1?20-1?200; IP: 1?500-1?2000

Manual	FNab09267.pdf

No Description Available.

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SKU	Supplier No.	Size	Your price	Quantity
BHA10809254	FNab09267	100ug	$240		Add to Cart

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