Thiol protease which recognizes and hydrolyzes the peptide bond at the C-terminal Gly of UFM1, a ubiquitin-like modifier protein bound to a number of target proteins. Does not hydrolyze SUMO1 or ISG15 ubiquitin-like proteins. Through TRIP4 deufmylation may regulate intracellular nuclear receptors transactivation and thereby regulate cell proliferation and differentiation.
Categories
Primary Antibodies
Cellular Localization
Cytoplasm, endoplasmic reticulum, Nucleus
Clonality
polyclonal
Description
Thiol protease which recognizes and hydrolyzes the peptide bond at the C-terminal Gly of UFM1, a ubiquitin-like modifier protein bound to a number of target proteins. Does not hydrolyze SUMO1 or ISG15 ubiquitin-like proteins. Through TRIP4 deufmylation may regulate intracellular nuclear receptors transactivation and thereby regulate cell proliferation and differentiation.
Host
Rabbit
Immunogen
UFM1-specific peptidase 2
Isotype
IgG
Molecular Weight
53 kDa
Reactivity
Human, Mouse, Rat
Regulatory
RUO
Subcellular Location
Cytoplasm, Endoplasmic reticulum, Nucleus
Synonyms
C4orf20, FLJ11200, UFM1 peptidase 2, Ufm1 specific protease 2, UFSP2
Uniprot
Q9NUQ7
Gene Id
55325
Research Area
Metabolism
Weight
53kDa
Form
liquid
Format
liquid
Purification
Immunogen affinity purified
Purity
>=95% as determined by SDS-PAGE
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)