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Home / Primary Antibodies / Polyclonal Antibodies

UCHL1/PGP9.5 antibody

SKU : BHA10809207

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Mfr.No.	FNab09218
Alternative Names	Neuroncytoplasmicprotein9.5 ; PARK5 ; PGP9.5 ; PGP9.5 ; UbiquitinthioesteraseL1 ; UchL1 ; UCHL1
Background	UCHL1(Ubiquitin carboxyl-terminal hydrolase isozyme L1) is a member of a gene family whose products hydrolyze small C-terminal adducts of ubiquitin to generate the ubiquitin monomer. Expression of UCHL1 is highly specific to neurons and to cells of the diffuse neuroendocrine system and their tumors. It is present in all neurons(PMID: 6343558). This protein is present in brain at concentrations at least 50 times greater than in other organs and is a major protein component of neuronal cytoplasm(PMID:7217993). And UCHL1 is a Parkinson's disease susceptibility gene(PMID:15048890).
Categories	Primary Antibodies
Cellular Localization	Cytoplasm, endoplasmic reticulum, Membrane
Clonality	polyclonal
Description	UCHL1(Ubiquitin carboxyl-terminal hydrolase isozyme L1) is a member of a gene family whose products hydrolyze small C-terminal adducts of ubiquitin to generate the ubiquitin monomer. Expression of UCHL1 is highly specific to neurons and to cells of the diffuse neuroendocrine system and their tumors. It is present in all neurons(PMID: 6343558). This protein is present in brain at concentrations at least 50 times greater than in other organs and is a major protein component of neuronal cytoplasm (PMID:7217993). And UCHL1 is a Parkinson's disease susceptibility gene (PMID:15048890).
Host	Rabbit
Immunogen	ubiquitin carboxyl-terminal esterase L1(ubiquitin thiolesterase)
Isotype	IgG
Molecular Weight	26 kDa
Reactivity	Human, Mouse, Rat
Regulatory	RUO
Subcellular Location	Cytoplasm, Endoplasmic reticulum, Membrane
Synonyms	Neuron cytoplasmic protein 9.5, PARK5, PGP 9.5, PGP9.5, Ubiquitin thioesterase L1, Uch L1, UCHL1

Uniprot	P09936
Gene Id	7345
Research Area	Epigenetics, Cancer, Metabolism, Neuroscience
Weight	26kDa

Form	liquid
Format	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)

Applications

ELISA, WB, IP

Description

ELISA ; WB ; IP

Dilution

WB	1:500-1:5000
IP	1:1000-1:10000

Tested Application

WB: 1:500-1:5000; IHC?1:100-1:500; IP: 1:1000-1:5000

Manual	FNab09218.pdf

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SKU	Supplier No.	Size	Your price	Quantity
BHA10809207	FNab09218	100ug	$260		Add to Cart

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