E3 ubiquitin-protein ligase which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N-terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation(By similarity).
Categories
Primary Antibodies
Clonality
polyclonal
Description
E3 ubiquitin-protein ligase which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N-terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation (By similarity).
Host
Rabbit
Immunogen
ubiquitin protein ligase E3 component n-recognin 7(putative)
Isotype
IgG
Molecular Weight
48 kDa
Reactivity
Human, Mouse, Rat
Regulatory
RUO
Synonyms
UBR7, FLJ10483, N recognin 7, C14orf130
Uniprot
Q8N806
Gene Id
55148
Research Area
Epigenetics, Metabolism
Weight
48kDa
Form
liquid
Format
liquid
Purification
Immunogen affinity purified
Purity
>=95% as determined by SDS-PAGE
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)