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Home / Primary Antibodies / Monoclonal Antibodies

UBE2C antibody

SKU : BHA10809158

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Mfr.No.	FNab09166
Alternative Names	DJ447F3.2 ; UBCH10 ; UBE2C ; UbiquitincarrierproteinC ; UbiquitinproteinligaseC
Background	Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro catalyzes 'Lys-11'-and 'Lys-48'-linked polyubiquitination. Acts as an essential factor of the anaphase promoting complex/cyclosome(APC/C), a cell cycle-regulated ubiquitin ligase that controls progression through mitosis. Acts by initiating 'Lys-11'-linked polyubiquitin chains on APC/C substrates, leading to the degradation of APC/C substrates by the proteasome and promoting mitotic exit.
Categories	Primary Antibodies
Cellular Localization	Cytoplasm, Uclear
Clonality	monoclonal
Description	Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro catalyzes 'Lys- 11'- and 'Lys-48'-linked polyubiquitination. Acts as an essential factor of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated ubiquitin ligase that controls progression through mitosis. Acts by initiating 'Lys-11'-linked polyubiquitin chains on APC/C substrates, leading to the degradation of APC/C substrates by the proteasome and promoting mitotic exit.
Host	Mouse
Immunogen	ubiquitin-conjugating enzyme E2C
Isotype	IgG1
Molecular Weight	17 kDa
Reactivity	Human
Regulatory	RUO
Subcellular Location	Cytoplasm,nuclear
Synonyms	DJ447F3.2, UBCH10, UBE2C, Ubiquitin carrier protein C, Ubiquitin protein ligase C

Uniprot	O00762
Gene Id	11065
Clone No	7E3
Research Area	Epigenetics, Metabolism
Weight	20kDa

Form	liquid
Format	liquid
Purification	Protein A+G purification
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)

Applications

ELISA, IF, IHC, WB

Description

ELISA ; IF ; IHC ; WB

Dilution

WB	1:500-1:5000
IHC	1:20-1:200
IF	1:10-1:100

Tested Application

WB: 1:500-1:2000; IHC: 1:20-1:200; IF: 1:10-1:100

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SKU	Supplier No.	Size	Your price	Quantity
BHA10809158	FNab09166	100ug	$300		Add to Cart

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