The heterodimer acts as a E1 ligase for SUMO1, SUMO2, SUMO3, and probably SUMO4. It mediates ATP-dependent activation of SUMO proteins followed by formation of a thioester bond between a SUMO protein and a conserved active site cysteine residue on UBA2/SAE2.
Categories
Primary Antibodies
Clonality
polyclonal
Description
The heterodimer acts as a E1 ligase for SUMO1, SUMO2, SUMO3, and probably SUMO4. It mediates ATP-dependent activation of SUMO proteins followed by formation of a thioester bond between a SUMO protein and a conserved active site cysteine residue on UBA2/SAE2.
Host
Rabbit
Immunogen
ubiquitin-like modifier activating enzyme 2
Isotype
IgG
Molecular Weight
90 kDa
Reactivity
Human, Mouse
Regulatory
RUO
Synonyms
ARX, FLJ13058, HRIHFB2115, SAE2, UBA2, UBLE1B
Uniprot
Q9UBT2
Gene Id
10054
Research Area
Epigenetics, Metabolism
Weight
71kDa,0beserved 90kDa
Form
liquid
Format
liquid
Purification
Immunogen affinity purified
Purity
>=95% as determined by SDS-PAGE
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)