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Home / Primary Antibodies / Polyclonal Antibodies

UACA antibody

SKU : BHA10809132

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Mfr.No.	FNab09140
Alternative Names	FLJ10128 ; KIAA1561 ; NUCLING ; UACA
Background	Regulates APAF1 expression and plays an important role in the regulation of stress-induced apoptosis. Promotes apoptosis by regulating three pathways, apoptosome up-regulation, LGALS3/galectin-3 down-regulation and NF-kappa-B inactivation. Regulates the redistribution of APAF1 into the nucleus after proapoptotic stress. Down-regulates the expression of LGALS3 by inhibiting NFKB1(By similarity). Modulates isoactin dynamics to regulate the morphological alterations required for cell growth and motility. Interaction with ARF6 may modulate cell shape and motility after injury. May be involved in multiple neurite formation(By similarity).
Categories	Primary Antibodies
Cellular Localization	Cytoplasm, cytoskeleton, Nucleus
Clonality	polyclonal
Description	Regulates APAF1 expression and plays an important role in the regulation of stress-induced apoptosis. Promotes apoptosis by regulating three pathways, apoptosome up-regulation, LGALS3/galectin-3 down-regulation and NF-kappa-B inactivation. Regulates the redistribution of APAF1 into the nucleus after proapoptotic stress. Down-regulates the expression of LGALS3 by inhibiting NFKB1 (By similarity). Modulates isoactin dynamics to regulate the morphological alterations required for cell growth and motility. Interaction with ARF6 may modulate cell shape and motility after injury. May be involved in multiple neurite formation (By similarity).
Host	Rabbit
Immunogen	uveal autoantigen with coiled-coil domains and ankyrin repeats
Isotype	IgG
Molecular Weight	163 kDa
Reactivity	Human, Mouse
Regulatory	RUO
Subcellular Location	Cytoplasm, Cytoskeleton, Nucleus
Synonyms	FLJ10128, KIAA1561, NUCLING, UACA

Uniprot	Q9BZF9
Gene Id	55075
Research Area	Cell Division and Proliferation, Immunology
Weight	163kDa

Form	liquid
Format	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)

Applications

ELISA, WB

Description

ELISA ; WB

Dilution

WB	1:1000-1:10000
IF	1:20-1:200

Tested Application

WB: 1:1000-1:10000; IF: 1:20-1:200

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SKU	Supplier No.	Size	Your price	Quantity
BHA10809132	FNab09140	100ug	$280		Add to Cart

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