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Home / Primary Antibodies / Polyclonal Antibodies

U2AF35 antibody

SKU : BHA10809129

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Mfr.No.	FNab09137
Alternative Names	DKFZp313J1712 ; FP793 ; RN ; RNU2AF1 ; U2AF1 ; U2AF35 ; U2AFBP
Background	This gene belongs to the splicing factor SR family of genes. U2 auxiliary factor, comprising a large and a small subunit, is a non-snRNP protein required for the binding of U2 snRNP to the pre-mRNA branch site. This gene encodes the small subunit which plays a critical role in both constitutive and enhancer-dependent RNA splicing by directly mediating interactions between the large subunit and proteins bound to the enhancers. Alternatively spliced transcript variants encoding different isoforms have been identified.
Categories	Primary Antibodies
Cellular Localization	Nucleus, Spliceosome
Clonality	polyclonal
Description	U2 auxiliary factor (U2AF), comprising a large and a small subunit, is a non-snRNP protein required for the binding of U2 snRNP to the pre-mRNA branch site. U2 (RNU2) small nuclear RNA auxiliary factor 1 (U2AF1,synonyms: RN, FP793, U2AF35, U2AFBP, RNU2AF1)is the small subunit which plays a critical role in both constitutive and enhancer-dependent RNA splicing by directly mediating interactions between the large subunit and proteins bound to the enhancers. The U2AF1 gene is localized to chromosome 21q22.3, which is the critical region for three diseases, progressive myoclonus epilepsy, autoimmune polyglandular disease type 1, and one form of bipolar affective disorder.
Host	Rabbit
Immunogen	U2 small nuclear RNA auxiliary factor 1
Isotype	IgG
Molecular Weight	38 kDa
Reactivity	Human, Mouse, Rat
Regulatory	RUO
Subcellular Location	Nucleus, Spliceosome
Synonyms	DKFZp313J1712, FP793, RN, RNU2AF1, U2AF1, U2AF35, U2AFBP

Uniprot	Q01081
Gene Id	7307
Research Area	Epigenetics, Metabolism, Neuroscience
Weight	28kDa,0beserved 40kDa

Form	liquid
Format	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Applications

ELISA, WB, IHC

Description

ELISA ; WB ; IHC

Dilution

WB	1:500-1:5000
IHC	1:20-1:200

Tested Application

WB: 1:500 - 1:2000; IHC: 1:50 - 1:200

Manual	FNab09137.pdf

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SKU	Supplier No.	Size	Your price	Quantity
BHA10809129	FNab09137	100ug	$260		Add to Cart

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