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Home / Primary Antibodies / Polyclonal Antibodies

TXNDC5 antibody

SKU : BHA10809119

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Mfr.No.	FNab09127
Alternative Names	EndoPDI ; ERprotein46 ; ERP46 ; Hcc2 ; PDIA15 ; Thioredoxinlikeproteinp46 ; TLP46 ; TXNDC5 ; UNQ364
Background	This gene encodes a member of the disulfide isomerase (PDI) family of endoplasmic reticulum (ER) proteins that catalyze protein folding and thiol-disulfide interchange reactions. The encoded protein has an N-terminal endoplasmic reticulum (ER)-signal sequence, three catalytically active thioredoxin domains and a C-terminal ER-retention sequence. Its expression is induced by hypoxia and its role may be to protect hypoxic cells from apoptosis. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the neighboring upstream BLOC1S5 gene.
Categories	Primary Antibodies
Cellular Localization	endoplasmic reticulum
Clonality	polyclonal
Description	Possesses thioredoxin activity. Has been shown to reduce insulin disulfide bonds. Also complements protein disulfide- isomerase deficiency in yeast (By similarity).
Host	Rabbit
Immunogen	thioredoxin domain containing 5 (endoplasmic reticulum)
Isotype	IgG
Molecular Weight	50 kDa
Reactivity	Human, Mouse, Rat
Regulatory	RUO
Subcellular Location	Endoplasmic reticulum
Synonyms	EndoPDI, ER protein 46, ERP46, Hcc 2, PDIA15, Thioredoxin like protein p46, TLP46, TXNDC5, UNQ364

Uniprot	Q8NBS9
Gene Id	81567
Research Area	Metabolism
Weight	48kDa

Form	liquid
Format	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.1% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Applications

ELISA, WB, IHC, IF

Description

ELISA ; WB ; IHC ; IF

Dilution

WB	1:1000-1:10000
IF	1:10-1:100
IHC	1:20-1:200

Tested Application

WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:50 - 1:100

Manual	FNab09127.pdf

No Description Available.

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SKU	Supplier No.	Size	Your price	Quantity
BHA10809119	FNab09127	100ug	$260		Add to Cart

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