Actin-binding protein involved in motile and morphological processes. Inhibits actin polymerization, likely by sequestering G-actin. By capping the barbed ends of filaments, it also regulates motility. Seems to play an important role in clathrin-mediated endocytosis and distribution of endocytic organelles(By similarity).
Categories
Primary Antibodies
Cellular Localization
Cytoplasm, cytoskeleton
Clonality
polyclonal
Description
Actin-binding protein involved in motile and morphological processes. Inhibits actin polymerization, likely by sequestering G-actin. By capping the barbed ends of filaments, it also regulates motility. Seems to play an important role in clathrin-mediated endocytosis and distribution of endocytic organelles (By similarity).
Host
Rabbit
Immunogen
twinfilin, actin-binding protein, homolog 1
Isotype
IgG
Molecular Weight
42 kDa
Reactivity
Human, Mouse, Rat
Regulatory
RUO
Subcellular Location
Cytoplasm, Cytoskeleton
Synonyms
TWF1, A6, Protein A6, Twinfilin 1, Protein tyrosine kinase 9
Uniprot
Q12792
Gene Id
5756
Research Area
Signal Transduction
Weight
42kDa
Form
liquid
Format
liquid
Purification
Immunogen affinity purified
Purity
>=95% as determined by SDS-PAGE
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)