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Home / Primary Antibodies / Polyclonal Antibodies

TTRAP antibody

SKU : BHA10809090

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Mfr.No.	FNab09098
Alternative Names	5TyrDNAphosphodiesterase ; AD022 ; dJ30M3.3 ; EAP2 ; EAPII ; ETS1associatedprotein2 ; ETS1associatedproteinII ; TDP2 ; TTRAP ; TyrDNAphosphodiesterase2
Background	TTRAP is a 5-prime tyrosyl-DNA phosphodiesterase that is required for efficient repair of topoisomerase II-induced DNA double-strand breaks. Thus it can remove lots of covalent adducts from DNA through hydrolysis of a 5'-phosphodiester bond, generating a free 5' phosphate to DNA. It also has 3'-tyrosyl DNA phophodiesterase activity, but not so efficient as TDP1. TTRAP functions as a negative regulator of ETS1 and inhibit nuclear factor-kappa-B activation.
Categories	Primary Antibodies
Clonality	polyclonal
Description	TTRAP is a 5-prime tyrosyl-DNA phosphodiesterase that is required for efficient repair of topoisomerase II-induced DNA double-strand breaks. Thus it can remove lots of covalent adducts from DNA through hydrolysis of a 5'-phosphodiester bond, generating a free 5' phosphate to DNA. It also has 3'-tyrosyl DNA phophodiesterase activity, but not so efficient as TDP1. TTRAP functions as a negative regulator of ETS1 and inhibit nuclear factor-kappa-B activation.
Host	Rabbit
Immunogen	TRAF and TNF receptor associated protein
Isotype	IgG
Molecular Weight	44 kDa
Reactivity	Human, Mouse, Rat
Regulatory	RUO
Synonyms	5 Tyr DNA phosphodiesterase, AD022, dJ30M3.3, EAP2, EAPII, ETS1 associated protein 2, ETS1 associated protein II, TDP2, TTRAP, Tyr DNA phosphodiesterase 2

Uniprot	O95551
Research Area	Signal Transduction
Weight	44kDa

Form	liquid
Format	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)

Applications

ELISA, WB, IP

Description

ELISA ; WB ; IP

Dilution

WB	1:500-1:5000
IP	1:200-1:2000

Tested Application

WB: 1:500-1:5000; IP: 1:200-1:2000

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SKU	Supplier No.	Size	Your price	Quantity
BHA10809090	FNab09098	100ug	$260		Add to Cart

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