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Home / Primary Antibodies / Polyclonal Antibodies

TTI1 antibody

SKU : BHA10809085

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Mfr.No.	FNab09093
Alternative Names	TELO2-interactingprotein1homolog ; KIAA0406 ; SMG10 ; TTI1
Background	Regulator of the DNA damage response(DDR). Part of the TTT complex that is required to stabilize protein levels of the phosphatidylinositol 3-kinase-related protein kinase(PIKK) family proteins. The TTT complex is involved in the cellular resistance to DNA damage stresses, like ionizing radiation(IR), ultraviolet(UV) and mitomycin C(MMC). Together with the TTT complex and HSP90 may participate in the proper folding of newly synthesized PIKKs. Promotes assembly, stabilizes and maintains the activity of mTORC1 and mTORC2 complexes, which regulate cell growth and survival in response to nutrient and hormonal signals.
Categories	Primary Antibodies
Clonality	polyclonal
Description	Regulator of the DNA damage response (DDR). Part of the TTT complex that is required to stabilize protein levels of the phosphatidylinositol 3-kinase-related protein kinase (PIKK) family proteins. The TTT complex is involved in the cellular resistance to DNA damage stresses, like ionizing radiation (IR), ultraviolet (UV) and mitomycin C (MMC). Together with the TTT complex and HSP90 may participate in the proper folding of newly synthesized PIKKs. Promotes assembly, stabilizes and maintains the activity of mTORC1 and mTORC2 complexes, which regulate cell growth and survival in response to nutrient and hormonal signals.
Host	Rabbit
Immunogen	KIAA0406
Isotype	IgG
Molecular Weight	122 kDa
Reactivity	Human
Regulatory	RUO
Synonyms	TELO2-interacting protein 1 homolog,KIAA0406, SMG10,TTI1

Uniprot	O43156
Gene Id	9675
Weight	122kDa

Form	liquid
Format	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)

Applications

ELISA, WB, IP

Description

ELISA ; WB ; IP

Dilution

WB	1:500-1:5000
IP	1:500-1:5000

Tested Application

WB: 1:500-1:5000; IP: 1:500-1:5000

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SKU	Supplier No.	Size	Your price	Quantity
BHA10809085	FNab09093	100ug	$280		Add to Cart

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