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Home / Primary Antibodies / Polyclonal Antibodies

TSHZ3 antibody

SKU : BHA10809038

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Mfr.No.	FNab09046
Alternative Names	FLJ54422 ; KIAA1474 ; Teashirthomolog3 ; TSH3 ; TSHZ3 ; Zincfingerprotein537 ; ZNF537
Background	Transcriptional regulator involved in developmental processes. Function in association with APBB1, SET and HDAC factors as a transcriptional repressor, that inhibits the expression of CASP4. TSHZ3-mediated transcription repression involves the recruitment of histone deacetylases HDAC1 and HDAC2. Associates with chromatin in a region surrounding the CASP4 transcriptional start site(s). Regulates the development of neurons involved in both respiratory rhythm and airflow control. Promotes maintenance of nucleus ambiguus(nA) motoneurons, which govern upper airway function, and establishes a respiratory rhythm generator(RRG) activity compatible with survival at birth. Involved in the differentiation of the proximal uretic smooth muscle cells during developmental processes. Involved in the up-regulation of myocardin, that directs the expression of smooth muscle cells in the proximal ureter.
Categories	Primary Antibodies
Clonality	polyclonal
Description	Transcriptional regulator involved in developmental processes. Function in association with APBB1, SET and HDAC factors as a transcriptional repressor, that inhibits the expression of CASP4. TSHZ3-mediated transcription repression involves the recruitment of histone deacetylases HDAC1 and HDAC2. Associates with chromatin in a region surrounding the CASP4 transcriptional start site(s). Regulates the development of neurons involved in both respiratory rhythm and airflow control. Promotes maintenance of nucleus ambiguus (nA) motoneurons, which govern upper airway function, and establishes a respiratory rhythm generator (RRG) activity compatible with survival at birth. Involved in the differentiation of the proximal uretic smooth muscle cells during developmental processes. Involved in the up- regulation of myocardin, that directs the expression of smooth muscle cells in the proximal ureter.
Host	Rabbit
Immunogen	teashirt zinc finger homeobox 3
Isotype	IgG
Molecular Weight	110 kDa
Reactivity	Human, Mouse
Regulatory	RUO
Synonyms	FLJ54422, KIAA1474, Teashirt homolog 3, TSH3, TSHZ3, Zinc finger protein 537, ZNF537

Uniprot	Q63HK5
Gene Id	57616
Research Area	Developmental biology, Metabolism
Weight	110kDa

Form	liquid
Format	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)

Applications

ELISA, WB

Description

ELISA ; WB

Dilution

WB	1:200-1:2000

Tested Application

WB: 1:200-1:2000

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SKU	Supplier No.	Size	Your price	Quantity
BHA10809038	FNab09046	100ug	$260		Add to Cart

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