The protein encoded by this gene is both an ion channel and a serine/threonine protein kinase. The kinase activity is essential for the ion channel function, which serves to increase intracellular calcium levels and to help regulate magnesium ion homeostasis. Defects in this gene are a cause of amyotrophic lateral sclerosis-parkinsonism/dementia complex of Guam. Alternative splicing of this gene results in multiple transcript variants.
Clonality
polyclonal
Host
Rabbit
Immunogen
Transient receptor potential cation channel subfamily M member 7
Immunogen Region
Transient receptor potential cation channel subfamily M member 7
Isotype
IgG
Molecular Weight
230 kDa
Reactivity
Mouse
Recommended Dilution
WB: 1:500-1:2000
Synonyms
TRPM7, ALSPDC, CHAK, CHAK1, LTRPC7
Uniprot
Q96QT4
Form
liquid
Purification
Immunogen affinity purified
Purity
>=95% as determined by SDS-PAGE
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)
Tested Application
WB: 1:500-1:2000
Product Manual
<a href="https://www.fn-test.com/content/uploads/product/manuals/antibody/FNab10501.pdf" target="_blank">Data Sheet</ a>