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Home / Primary Antibodies / Monoclonal Antibodies

TRPC4AP antibody

SKU : BHA10809009

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Mfr.No.	FNab09017
Alternative Names	C20orf188 ; ProteinTAP1 ; ProteinTRUSS ; Trp4associatedprotein ; Trpc4associatedprotein ; TRPC4AP ; TRRP4AP ; TRUSS
Background	Substrate-specific adapter of a DCX(DDB1-CUL4-X-box) E3 ubiquitin-protein ligase complex required for cell cycle control. The DCX(TRUSS) complex specifically mediates the polyubiquitination and subsequent degradation of MYC. Also participates in the activation of NFKB1 in response to ligation of TNFRSF1A, possibly by linking TNFRSF1A to the IKK signalosome. Involved in JNK activation via its interaction with TRAF2. Also involved in elevation of endoplasmic reticulum Ca(2+) storage reduction in response to CHRM1.
Categories	Primary Antibodies
Cellular Localization	Cul4A-Ring E3 Ubiquitin Ligase Complex, Membrane
Clonality	monoclonal
Description	Substrate-specific adapter of a DCX (DDB1-CUL4-X-box) E3 ubiquitin-protein ligase complex required for cell cycle control. The DCX(TRUSS) complex specifically mediates the polyubiquitination and subsequent degradation of MYC. Also participates in the activation of NFKB1 in response to ligation of TNFRSF1A, possibly by linking TNFRSF1A to the IKK signalosome. Involved in JNK activation via its interaction with TRAF2. Also involved in elevation of endoplasmic reticulum Ca(2+) storage reduction in response to CHRM1.
Host	Mouse
Immunogen	transient receptor potential cation channel, subfamily C, member 4 associated protein
Isotype	IgG1
Molecular Weight	91 kDa
Reactivity	Human
Regulatory	RUO
Subcellular Location	Cul4A-RING E3 ubiquitin ligase complex,plasma membrane
Synonyms	C20orf188, Protein TAP1, Protein TRUSS, Trp4 associated protein, Trpc4 associated protein, TRPC4AP, TRRP4AP, TRUSS

Uniprot	Q8TEL6
Gene Id	26133
Clone No	1C0
Research Area	Signal Transduction
Weight	91kDa

Form	liquid
Format	liquid
Purification	Protein A+G purification
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)

Applications

ELISA, WB, IHC

Description

ELISA ; WB ; IHC

Dilution

WB	1:500-1:5000
IHC	1:20-1:200

Tested Application

WB: 1:500-1:5000; IHC: 1:20-1:200

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SKU	Supplier No.	Size	Your price	Quantity
BHA10809009	FNab09017	100ug	$300		Add to Cart

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