Thought to form a receptor-activated non-selective calcium permeant cation channel. Probably is operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G-protein coupled receptors. Seems to be also activated by intracellular calcium store depletion.
Categories
Primary Antibodies
Clonality
polyclonal
Description
Thought to form a receptor-activated non-selective calcium permeant cation channel. Probably is operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G-protein coupled receptors. Seems to be also activated by intracellular calcium store depletion.
Host
Rabbit
Immunogen
transient receptor potential cation channel, subfamily C, member 1
Isotype
IgG
Molecular Weight
91 kDa
Reactivity
Human, Mouse, Rat
Regulatory
RUO
Synonyms
HTRP 1, Transient receptor protein 1, TRP 1, TRP1, TRPC1
Uniprot
P48995
Gene Id
7220
Research Area
Cardiovascular, Signal Transduction, Neuroscience
Weight
91kDa,Observed 130kDa
Form
liquid
Format
liquid
Purification
Immunogen affinity purified
Purity
>=95% as determined by SDS-PAGE
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)