E3 ubiquitin-protein ligase which ubiquitinates itself in cooperation with an E2 enzyme UBE2D2/UBC4 and serves as a targeting signal for proteasomal degradation. May play a role in regulation of neuronal functions and may also participate in the formation or breakdown of abnormal inclusions in neurodegenerative disorders. May act as a regulator of synaptic vesicle exocytosis by controlling the availability of SNAP25 for the SNARE complex formation.
Categories
Primary Antibodies
Clonality
polyclonal
Description
E3 ubiquitin-protein ligase which ubiquitinates itself in cooperation with an E2 enzyme UBE2D2/UBC4 and serves as a targeting signal for proteasomal degradation. May play a role in regulation of neuronal functions and may also participate in the formation or breakdown of abnormal inclusions in neurodegenerative disorders. May act as a regulator of synaptic vesicle exocytosis by controlling the availability of SNAP25 for the SNARE complex formation.
Host
Rabbit
Immunogen
tripartite motif-containing 9
Isotype
IgG
Molecular Weight
60 kDa, 80 kDa
Reactivity
Human, Mouse, Rat
Regulatory
RUO
Synonyms
KIAA0282, RING finger protein 91, RNF91, SPRING, TRIM9, tripartite motif containing 9
Uniprot
Q9C026
Gene Id
114088
Research Area
Epigenetics, Signal Transduction, Metabolism, Neuroscience
Weight
80kDa,Observed 60kDa
Form
liquid
Format
liquid
Purification
Immunogen affinity purified
Purity
>=95% as determined by SDS-PAGE
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)