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Home / Primary Antibodies / Polyclonal Antibodies

TRIM25 antibody

SKU : BHA10808968

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Mfr.No.	FNab08976
Alternative Names	EFP ; RINGfingerprotein147 ; RNF147 ; TRIM25 ; tripartitemotifcontaining25 ; Z147 ; Zincfingerprotein147 ; ZNF147
Background	Functions as a ubiquitin E3 ligase and as an ISG15 E3 ligase. Involved in innate immune defense against viruses by mediating ubiquitination of DDX58. Mediates 'Lys-63'-linked polyubiquitination of the DDX58 N-terminal CARD-like region which is crucial for triggering the cytosolic signal transduction that leads to the production of interferons in response to viral infection. Promotes ISGylation of 14-3-3 sigma(SFN), an adapter protein implicated in the regulation of a large spectrum signaling pathway. Mediates estrogen action in various target organs. Mediates the ubiquitination and subsequent proteasomal degradation of ZFHX3(PubMed:22452784).
Categories	Primary Antibodies
Clonality	polyclonal
Description	Functions as a ubiquitin E3 ligase and as an ISG15 E3 ligase. Involved in innate immune defense against viruses by mediating ubiquitination of DDX58. Mediates 'Lys-63'-linked polyubiquitination of the DDX58 N-terminal CARD-like region which is crucial for triggering the cytosolic signal transduction that leads to the production of interferons in response to viral infection. Promotes ISGylation of 14-3-3 sigma (SFN), an adapter protein implicated in the regulation of a large spectrum signaling pathway. Mediates estrogen action in various target organs. Mediates the ubiquitination and subsequent proteasomal degradation of ZFHX3 (PubMed:22452784).
Host	Rabbit
Immunogen	tripartite motif-containing 25
Isotype	IgG
Molecular Weight	71 kDa
Reactivity	Human, Mouse
Regulatory	RUO
Synonyms	EFP,RING finger protein 147, RNF147, TRIM25, tripartite motif containing 25, Z147, Zinc finger protein 147, ZNF147

Uniprot	Q14258
Gene Id	7706
Research Area	Epigenetics, Immunology, Metabolism
Weight	71kDa

Form	liquid
Format	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)

Applications

ELISA, WB, IF, IP

Description

ELISA ; WB ; IF ; IP

Dilution

WB	1:200-1:2000
IP	1:200-1:2000
IF	1:20-1:200

Tested Application

WB: 1:200-1:2000; IP: 1:200-1:2000; IF: 1:20-1:200

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SKU	Supplier No.	Size	Your price	Quantity
BHA10808968	FNab08976	100ug	$280		Add to Cart

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