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Home / Primary Antibodies / Polyclonal Antibodies

TRIM24 antibody

SKU : BHA10808967

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Mfr.No.	FNab08975
Alternative Names	HTIF1 ; PTC6 ; RINGfingerprotein82 ; RNF82 ; TF1A ; TIF1 ; TIF1alpha ; TIF1A ; TIF1ALPHA ; TRIM24 ; tripartitemotifcontaining24
Background	Transcriptional coactivator that interacts with numerous nuclear receptors and coactivators and modulates the transcription of target genes. Interacts with chromatin depending on histone H3 modifications, having the highest affinity for histone H3 that is both unmodified at 'Lys-4'(H3K4me0) and acetylated at 'Lys-23'(H3K23ac). Has E3 protein-ubiquitin ligase activity. Promotes ubiquitination and proteasomal degradation of p53/TP53. Plays a role in the regulation of cell proliferation and apoptosis, at least in part via its effects on p53/TP53 levels. Up-regulates ligand-dependent transcription activation by AR, GCR/NR3C1, thyroid hormone receptor(TR) and ESR1. Modulates transcription activation by retinoic acid(RA) receptors, including RARA. Plays a role in regulating retinoic acid-dependent proliferation of hepatocytes(By similarity).
Categories	Primary Antibodies
Clonality	polyclonal
Description	Transcriptional coactivator that interacts with numerous nuclear receptors and coactivators and modulates the transcription of target genes. Interacts with chromatin depending on histone H3 modifications, having the highest affinity for histone H3 that is both unmodified at 'Lys-4' (H3K4me0) and acetylated at 'Lys-23' (H3K23ac). Has E3 protein-ubiquitin ligase activity. Promotes ubiquitination and proteasomal degradation of p53/TP53. Plays a role in the regulation of cell proliferation and apoptosis, at least in part via its effects on p53/TP53 levels. Up-regulates ligand-dependent transcription activation by AR, GCR/NR3C1, thyroid hormone receptor (TR) and ESR1. Modulates transcription activation by retinoic acid (RA) receptors, including RARA. Plays a role in regulating retinoic acid-dependent proliferation of hepatocytes (By similarity).
Host	Rabbit
Immunogen	tripartite motif-containing 24
Isotype	IgG
Molecular Weight	117 kDa
Reactivity	Human, Mouse, Rat
Regulatory	RUO
Synonyms	HTIF1, PTC6, RING finger protein 82, RNF82, TF1A, TIF1, TIF1 alpha, TIF1A, TIF1ALPHA, TRIM24, tripartite motif containing 24

Antigen	TRIM24
Uniprot	O15164
Gene Id	8805
Research Area	Metabolism
Weight	116kDa

Form	liquid
Format	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)

Applications

ELISA, WB, IHC, IP

Description

ELISA ; WB ; IHC ; IP

Dilution

WB	1:500-1:5000
IP	1:200-1:2000
IHC	1:50-1:200
IF	1:50-1:500

Tested Application

WB: 1:500-1:5000; IP: 1:200-1:2000; IHC: 1:50-1:200; IF: 1:50-1:500

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SKU	Supplier No.	Size	Your price	Quantity
BHA10808967	FNab08975	100ug	$260		Add to Cart

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