Acts as an E3 ubiquitin-protein ligase. In the presence of the human cytomegalovirus(HCMV) protein UL144, participates in 'Lys-63'-linked auto-ubiquitination of TRAF6 resulting in the virally controlled activation of NF-kappa-B at early time of infection. The C-terminus can act as an allosteric activator of the cholera toxin catalytic subunit.
Categories
Primary Antibodies
Clonality
polyclonal
Description
Acts as an E3 ubiquitin-protein ligase. In the presence of the human cytomegalovirus (HCMV) protein UL144, participates in 'Lys-63'-linked auto-ubiquitination of TRAF6 resulting in the virally controlled activation of NF-kappa-B at early time of infection. The C-terminus can act as an allosteric activator of the cholera toxin catalytic subunit.
Host
Rabbit
Immunogen
tripartite motif-containing 23
Isotype
IgG
Molecular Weight
64 kDa
Reactivity
Human, Mouse, Rat
Regulatory
RUO
Synonyms
ARD1, ARFD1, GTP binding protein ARD 1, RING finger protein 46, RNF46, TRIM23, tripartite motif containing 23
Uniprot
P36406
Gene Id
373
Research Area
Epigenetics
Weight
64kDa
Form
liquid
Format
liquid
Purification
Immunogen affinity purified
Purity
>=95% as determined by SDS-PAGE
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)