UBE2D1-dependent E3 ubiquitin-protein ligase that mediates the ubiquitination of NEFL and of phosphorylated BCL2L11. Plays a neuroprotective function. May play a role in neuronal rapid ischemic tolerance.
Categories
Primary Antibodies
Cellular Localization
Cytoplasm
Clonality
polyclonal
Description
UBE2D1-dependent E3 ubiquitin-protein ligase that mediates the ubiquitination of NEFL and of phosphorylated BCL2L11. Plays a neuroprotective function. May play a role in neuronal rapid ischemic tolerance.
Host
Rabbit
Immunogen
tripartite motif-containing 2
Isotype
IgG
Molecular Weight
70-82 kDa
Reactivity
Human, Mouse, Rat
Regulatory
RUO
Subcellular Location
Cytoplasm
Synonyms
KIAA0517, RING finger protein 86, RNF86, TRIM2, tripartite motif containing 2
Uniprot
Q9C040
Gene Id
23321
Research Area
Developmental biology, Metabolism
Weight
82kDa,85kDa
Form
liquid
Format
liquid
Purification
Immunogen affinity purified
Purity
>=95% as determined by SDS-PAGE
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)