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Home / Primary Antibodies / Polyclonal Antibodies

Trefoil factor 3 antibody

SKU : BHA10808951

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Mfr.No.	FNab08959
Alternative Names	HITF ; hP1.B ; Intestinaltrefoilfactor ; ITF ; PolypeptideP1.B ; TFF3 ; TFI ; Trefoilfactor3 ; trefoilfactor3(intestinal)
Background	Members of the trefoil family are characterized by having at least one copy of the trefoil motif, a 40-amino acid domain that contains three conserved disulfides. They are stable secretory proteins expressed in gastrointestinal mucosa. Their functions are not defined, but they may protect the mucosa from insults, stabilize the mucus layer and affect healing of the epithelium. This gene is expressed in goblet cells of the intestines and colon. This gene and two other related trefoil family member genes are found in a cluster on chromosome 21.
Categories	Primary Antibodies
Clonality	polyclonal
Description	Trefoil factor 3 (TFF3) belongs to the TFF-domain peptide family which consists of three small secreted proteins (TFF1, TFF2, TFF3) that are expressed by mucous-secreting epithelia. TFF3 is a major constituent in the goblet cells in small and large intestines, especially a typical secretary peptide of the normal human antral and pyloric gastric mucosa. TFF3 is essential in regulating cell migration and maintaining normal GI mucosal integrity. TFF3 has been reported to be overexpressed at the gene and the protein level in human neoplasms such as prostate, breast, and colon cancer. TFF3 is involved in tumor cell scattering, angiogenesis, and invasion.
Host	Rabbit
Immunogen	trefoil factor 3 (intestinal)
Isotype	IgG
Molecular Weight	18 kDa
Reactivity	Human, Mouse
Regulatory	RUO
Synonyms	HITF, hP1.B, Intestinal trefoil factor, ITF, Polypeptide P1.B, TFF3, TFI, Trefoil factor 3, trefoil factor 3 (intestinal)

Uniprot	Q07654
Gene Id	7033
Research Area	Developmental biology, Cancer, Signal Transduction, Metabolism
Weight	9kDa

Form	liquid
Format	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Applications

ELISA, IHC

Description

ELISA ; IHC

Dilution

WB	1:200-1:2000
IHC	1:50-1:500

Tested Application

WB: 1:500 - 1:2000; IHC: 1:50 - 1:200

Manual	FNab08959.pdf

No Description Available.

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SKU	Supplier No.	Size	Your price	Quantity
BHA10808951	FNab08959	100ug	$280		Add to Cart

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