Necessary for collagen type I synthesis. May couple the activity of the ER Ca(2+) pump SERCA2B with the activity of the translocon. This coupling may increase the local Ca(2+) concentration at the site of collagen synthesis, and a high Ca(2+) concentration may be necessary for the function of molecular chaperones involved in collagen folding.
Categories
Primary Antibodies
Clonality
polyclonal
Description
Necessary for collagen type I synthesis. May couple the activity of the ER Ca(2+) pump SERCA2B with the activity of the translocon. This coupling may increase the local Ca(2+) concentration at the site of collagen synthesis, and a high Ca(2+) concentration may be necessary for the function of molecular chaperones involved in collagen folding.
Host
Rabbit
Immunogen
translocation associated membrane protein 2
Isotype
IgG
Molecular Weight
43 kDa
Reactivity
Human, Mouse, Rat
Regulatory
RUO
Synonyms
KIAA0057
Uniprot
Q15035
Gene Id
9697
Research Area
Metabolism
Weight
43kDa,observed 43kDa,66kDa
Form
liquid
Format
liquid
Purification
Immunogen affinity purified
Purity
>=95% as determined by SDS-PAGE
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)