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Home / Primary Antibodies / Polyclonal Antibodies

TRADD antibody

SKU : BHA10810235

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Mfr.No.	FNab10260
Background	The nuclear form acts as a tumor suppressor by preventing ubiquitination and degradation of isoform p19ARF/ARF of CDKN2A by TRIP12: acts by interacting with TRIP12, leading to disrupt interaction between TRIP12 and isoform p19ARF/ARF of CDKN2A(By similarity). Adapter molecule for TNFRSF1A/TNFR1 that specifically associates with the cytoplasmic domain of activated TNFRSF1A/TNFR1 mediating its interaction with FADD. Overexpression of TRADD leads to two major TNF-induced responses, apoptosis and activation of NF-kappa-B.
Clonality	polyclonal
Host	Rabbit
Immunogen	TNFRSF1A-associated via death domain
Immunogen Region	TNFRSF1A-associated VIa death domain
Isotype	IgG
Molecular Weight	34 kDa, 27 kDa
Reactivity	Human, Mouse, Rat
Recommended Dilution	WB: 1:200 - 1:2000; IHC: 1:50 - 1:500
Synonyms	Hs.89862, TRADD

Uniprot	Q15628
Gene Id	8717
Research Area	Signal Transduction

Form	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)

Tested Application	WB: 1:200 - 1:2000; IHC: 1:50 - 1:500

Product Manual	<a href="https://www.fn-test.com/content/uploads/product/manuals/antibody/FNab10260.pdf" target="_blank">Data Sheet</ a>

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SKU	Supplier No.	Size	Your price	Quantity
BHA10810235	FNab10260	100ug	$260		Add to Cart

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