This gene encodes a member of the pterin-dependent aromatic acid hydroxylase family. The encoded protein catalyzes the first and rate limiting step in the biosynthesis of serotonin, an important hormone and neurotransmitter. Mutations in this gene may be associated with psychiatric diseases such as bipolar affective disorder and major depression.
Categories
Primary Antibodies
Clonality
polyclonal
Host
Rabbit
Immunogen
tryptophan hydroxylase 2
Isotype
IgG
Molecular Weight
56 kDa
Reactivity
Human, Rat, Mouse
Regulatory
RUO
Synonyms
NTPH
Uniprot
Q8IWU9
Gene Id
121278
Research Area
Signal Transduction, Metabolism, Neuroscience
Form
liquid
Format
liquid
Purification
Immunogen affinity purified
Purity
>=95% as determined by SDS-PAGE
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)