Receptor for TNFSF13/APRIL and TNFSF13B/TALL1/BAFF/BLYS that binds both ligands with similar high affinity. Mediates calcineurin-dependent activation of NF-AT, as well as activation of NF-kappa-B and AP-1. Involved in the stimulation of B-and T-cell function and the regulation of humoral immunity.
Categories
Primary Antibodies
Clonality
polyclonal
Description
Receptor for TNFSF13/APRIL and TNFSF13B/TALL1/BAFF/BLYS that binds both ligands with similar high affinity. Mediates calcineurin-dependent activation of NF-AT, as well as activation of NF-kappa-B and AP-1. Involved in the stimulation of B- and T- cell function and the regulation of humoral immunity.
Host
Rabbit
Immunogen
tumor necrosis factor receptor superfamily, member 13B
Isotype
IgG
Molecular Weight
30-32 kDa
Reactivity
Human
Regulatory
RUO
Synonyms
TACI
Antigen
TNFRSF13B
Uniprot
O14836
Gene Id
23495
Research Area
Immunology, Signal Transduction
Form
liquid
Format
liquid
Purification
Immunogen affinity purified
Purity
>=95% as determined by SDS-PAGE
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)