Key component of innate and adaptive immunity. TLRs(Toll-like receptors) control host immune response against pathogens through recognition of molecular patterns specific to microorganisms. TLR7 is a nucleotide-sensing TLR which is activated by single-stranded RNA. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response(By similarity).
Categories
Primary Antibodies
Clonality
polyclonal
Description
Key component of innate and adaptive immunity. TLRs (Toll-like receptors) control host immune response against pathogens through recognition of molecular patterns specific to microorganisms. TLR7 is a nucleotide-sensing TLR which is activated by single-stranded RNA. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response (By similarity).
Host
Rabbit
Immunogen
toll-like receptor 7
Isotype
IgG
Molecular Weight
121kd
Reactivity
Human, Mouse, Rat
Regulatory
RUO
Synonyms
TLR7, toll like receptor 7
Uniprot
Q9NYK1
Gene Id
51284
Research Area
Developmental biology, Immunology, Signal Transduction
Form
liquid
Format
liquid
Purification
Immunogen affinity purified
Purity
>=95% as determined by SDS-PAGE
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)