Participates in the innate immune response to microbial agents. Mediates detection of bacterial flagellins. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response.
Categories
Primary Antibodies
Clonality
polyclonal
Description
Participates in the innate immune response to microbial agents. Mediates detection of bacterial flagellins. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response.
Host
Rabbit
Immunogen
toll-like receptor 5
Isotype
IgG
Molecular Weight
97 kDa
Reactivity
Human, Mouse
Regulatory
RUO
Synonyms
TIL3
Uniprot
O60602
Gene Id
7100
Research Area
Developmental biology, Immunology, Signal Transduction
Form
liquid
Format
liquid
Purification
Immunogen affinity purified
Purity
>=95% as determined by SDS-PAGE
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)