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Home / Primary Antibodies / Monoclonal Antibodies

TLR4 antibody

SKU : BHA10809829

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Mfr.No.	FNab09837
Background	TLR4, also named as CD284, belongs to the Toll-like receptor family. TLR4 cooperates with LY96 and CD14 to mediates the innate immune response to bacterial lipopolysaccharide (LPS). TLR4 acts via MYD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Three alternatively spliced transcript variants that encode different protein isoforms have been described.
Clonality	monoclonal
Host	Mouse
Immunogen	toll-like receptor 4
Immunogen Region	toll-like receptor 4
Isotype	IgG2b
Molecular Weight	100 kDa
Reactivity	Human, Mouse, Rat
Recommended Dilution	WB: 1:1000-1:8000; IHC: 1:50-1:500
Synonyms	ARMD10, CD284, hToll, TLR4, TOLL, toll like receptor 4

Uniprot	O00206
Gene Id	7099
Clone No	3E7
Research Area	Developmental biology, Immunology, Signal Transduction, Neuroscience

Form	liquid
Purification	Protein A+G purification
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)

Tested Application	WB: 1:1000-1:8000; IHC: 1:50-1:500

Product Manual	<a href="https://www.fn-test.com/content/uploads/product/manuals/antibody/FNab09837.pdf" target="_blank">Data Sheet</ a>

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SKU	Supplier No.	Size	Your price	Quantity
BHA10809829	FNab09837	100ug	$280		Add to Cart

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