Transcriptional corepressor that binds to a number of transcription factors. Inhibits the transcriptional activation mediated by CTNNB1 and TCF family members in Wnt signaling. The effects of full-length TLE family members may be modulated by association with dominant-negative AES(By similarity).
Categories
Primary Antibodies
Clonality
polyclonal
Description
Transcriptional corepressor that binds to a number of transcription factors. Inhibits the transcriptional activation mediated by CTNNB1 and TCF family members in Wnt signaling. The effects of full-length TLE family members may be modulated by association with dominant-negative AES (By similarity).
Host
Rabbit
Immunogen
transducin-like enhancer of split 3(E(sp1) homolog, Drosophila)
Isotype
IgG
Molecular Weight
90 kDa
Reactivity
Human, Mouse, Rat
Regulatory
RUO
Synonyms
KIAA1547
Uniprot
Q04726
Gene Id
7090
Research Area
Developmental biology, Stem Cells, Signal Transduction, Metabolism
Form
liquid
Format
liquid
Purification
Immunogen affinity purified
Purity
>=95% as determined by SDS-PAGE
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)